Sandimmune (Cyclosporine (Ciclosporin))
Sorry, we currently do not carry this product.
Cyclosporine (Ciclosporin) Information
(sye' kloe spor een)Cyclosporine injection must be given under the supervision of a doctor who is experienced in treating transplant patients and prescribing medications that decrease the activity of the immune system. Receiving cyclosporine injection may increase the risk that you will develop an infection or cancer, especially lymphoma (cancer of a part of the immune system) or skin cancer. This risk may be higher if you receive cyclosporine injection with other medications that decrease the activity of the immune system such as azathioprine (Imuran), cancer chemotherapy, methotrexate (Rheumatrex), sirolimus (Rapamune), and tacrolimus (Prograf). Tell your doctor if you are taking any of these medications, and if you have or have ever had any type of cancer. If you experience any of the following symptoms, call your doctor immediately: sore throat, fever, chills, and other signs of infection; flu-like symptoms; coughing; difficulty urinating; pain when urinating; a red, raised, or swollen area on the skin; new sores or discoloration on the skin; lumps or masses anywhere in your body; night sweats; swollen glands in the neck, armpits, or groin; difficulty breathing; chest pain; weakness or tiredness that does not go away; or pain, swelling, or fullness in the stomach. Talk to your doctor about the risks of receiving cyclosporine injection.
Before receiving cyclosporine injection,
- tell your doctor and pharmacist if you are allergic to cyclosporine (Gengraf, Neoral, Sandimmune), any other medications, or Cremophor EL.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking, or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: acyclovir (Zovirax); allopurinol (Zyloprim); amiodarone (Cordarone); amphotericin B (Amphotec, Fungizone); angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); angiotensin II receptor antagonists such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), and valsartan (Diovan); certain antifungal medications such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); azithromycin (Zithromax); bromocriptine (Parlodel); calcium channel blockers such as diltiazem (Cardizem), nicardipine (Cardene), nifedipine (Adalat, Procardia),and verapamil (Calan); carbamazepine (Carbitrol, Epitol, Tegretol); cholesterol-lowering medications (statins) such as atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and simvastatin (Zocor); cimetidine (Tagamet);ciprofloxacin (Cipro); clarithromycin (Biaxin); colchicine; dalfopristin and quinupristin combination (Synercid); danazol; digoxin (Lanoxicaps, Lanoxin); certain diuretics ('water pills') including amiloride (in Hydro-ride), spironolactone (Aldactone), and triamterene (Dyazide, Dyrenium, in Maxzide); erythromycin (E.E.S., E-Mycin, Erythrocin); fenofibrate (Antara, Lipophen, Tricor); gentamicin; HIV protease inhibitors such as indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, in Kaletra), and saquinavir (Fortovase); imatinib (Gleevec); metoclopramide (Reglan); methylprednisolone (Medrol); nafcillin; nonsteroidal anti-inflammatory medications such as diclofenac (Cataflam, Voltaren), naproxen (Aleve, Naprosyn), and sulindac (Clinoril); octreotide (Sandostatin); hormonal contraceptives (birth control pills, patches, implants, and injections);orlistat (alli, Xenical); potassium supplements; prednisolone (Pediapred); phenobarbital; phenytoin (Dilantin); ranitidine (Zantac); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane); sulfinpyrazone (Anturane); terbinafine (Lamisil); ticlopidine (Ticlid); tobramycin (Tobi); trimethoprim with sulfamethoxazole (Bactrim, Septra); and vancomycin (Vancocin). Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
- tell your doctor what herbal products you are taking or plan to take, especially St. John's wort.
- tell your doctor if you are being treated with phototherapy (a treatment for psoriasis that involves exposing the skin to ultraviolet light) and if you have or have ever had low levels of cholesterol or magnesium in your blood or high blood pressure.
- tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while receiving cyclosporine injection, call your doctor. Cyclosporine injection may increase the risk that your baby will be born too early.
- tell your doctor if you are breast-feeding or planning to breastfeed.
- do not have vaccinations without talking to your doctor.
- you should know that cyclosporine may cause extra tissue to grow in your gums. Be sure to brush your teeth carefully and see a dentist regularly during your treatment to decrease the risk that you will develop this side effect.
- increased hair growth on the face, arms, and back
- swelling of gum tissue, or growth of extra tissue on the gums
- uncontrollable shaking of a part of your body
- pain, burning, numbness, or tingling in the hands, arms, feet, or legs
- breast enlargement in men
- flushing of the face or chest
- shortness of breath
- fast heartbeat
- difficulty swallowing
- loss of consciousness
- changes in mood or behavior
- difficulty moving
- vision problems or sudden blackouts
- swelling of the hands, arms, feet, ankles, or lower legs