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Amikin (Amikacin Sulfate)
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Amikacin Sulfate Information
(am i kay' sin)Amikacin may cause serious kidney problems. Kidney problems may occur more often in older people or in people that are dehydrated. Tell your doctor if you have or have ever had kidney disease. If you experience any of the following symptoms, call your doctor immediately: decreased urination; swelling of the face, arms, hands, feet, ankles, or lower legs; or unusual tiredness or weakness. Amikacin may cause serious hearing problems. Hearing problems may occur more often in older people or in people that are dehydrated. Hearing loss may be permanent in some cases. Tell your doctor if you have or have ever had dizziness, vertigo, hearing loss, or ringing in the ears. If you experience any of the following symptoms, call your doctor immediately: hearing loss, roaring or ringing in the ears, or dizziness. Amikacin may cause nerve problems. Tell your doctor if you have or have ever had burning, tingling, or numbness in the hands, arms, feet, or legs; muscle twitching or weakness; or seizures. The risk that you will develop serious kidney, hearing, or other problems is greater if you are taking certain medications. Tell your doctor and pharmacist if you are taking acyclovir (Zovirax, Sitavig); amphotericin (Abelcet, Ambisome, Amphotec); bacitracin; capreomycin (Capastat); certain cephalosporin antibiotics such as cefazolin (Ancef, Kefzol), cefixime (Suprax), or cephalexin (Keflex); cisplatin; colistin (Coly-Mycin S); cyclosporine (Gengraf, Neoral, Restasis, Sandimmune); diuretics ('water pills') such as bumetanide, ethacrynic acid (Edecrin), furosemide (Lasix), or torsemide (Demadex); other aminoglycoside antibiotics such as gentamicin, kanamycin, neomycin (Neo-Fradin), paromomycin, streptomycin or tobramycin; polymyxin B; or vancomycin (Vanocin). Your doctor may not want you to receive amikacin injection. If you are having surgery, including dental surgery, tell the doctor or dentist that you are using amikacin injection. Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests, including hearing tests, before and during treatment to check your body's response to amikacin.
Before receiving amikacin injection,
- tell your doctor and pharmacist if you are allergic to amikacin injection; other aminoglycoside antibiotics such as gentamicin, kanamycin, neomycin, streptomycin, or tobramycin; sulfites; any other medications; or any of the ingredients in amikacin injection. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements, you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics such as amoxicillin (Amoxil, Larotid, Moxatag, in Augmentin, in Prevpac), ampicillin, or penicillin; dimenhydrinate (Dramamine); meclizine (Bonine); or nonsteroidal anti-inflammatory drugs such as indomethacin (Indocin, Tivorbex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with amikacin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you are or have or have ever had cystic fibrosis (an inherited condition that affects the lungs and digestive system), problems with your muscles such as myasthenia gravis or Parkinson's disease.
- Tell your doctor if you are pregnant or plan to become pregnant or breastfeed. If you become pregnant while using amikacin injection, call your doctor immediately. Amikacin may harm the fetus.
- peeling or blistering of the skin
- swelling of the eyes, face, throat, tongue, or lips
- difficulty breathing or swallowing
- severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after your treatment)