Before taking netupitant and palonosetron,
tell your doctor and pharmacist if you are allergic to netupitant and palonosetron, alosetron (Lotronex), dolasetron (Anzemet), granisetron (Sancuso), ondansetron (Zofran, Zuplenz), any other medications, or any of the ingredients in netupitant and palonosetron capsules. Ask your pharmacist for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: benzodiazepines including alprazolam (Xanax), midazolam, and triazolam (Halcion); certain chemotherapy medications such as cyclophosphamide (Cytoxan), docetaxel (Docefrez, Taxotere), etoposide, ifosfamide (Ifex), imatinib (Gleevec), irinotecan (Camptosar), paclitaxel (Taxol), vinblastine, vincristine, and vinorelbine (Navelbine); dexamethasone; erythromycin (E.E.S., Ery-tab, others); fentanyl (Abstral, Actiq, Duragesic, Fentora, Lazanda, Onsolis, Subsys); ketoconazole (Nizoral); lithium (Lithobid); medications to treat migraines such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig); methylene blue; mirtazapine (Remeron); monoamine oxidase (MAO) inhibitors including isocarboxazid (Marplan), linezolid (Zyvox), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate); phenobarbital; rifampin (Rifadin, Rimactane, in Rifater, in Rifamate); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), and sertraline (Zoloft); and tramadol (Conzip, Ultram, in Ultracet). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor if you have or have ever had liver or kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking netupitant and palonosetron, call your doctor.