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Gleevec (Imatinib Mesylate)

Glivec
100mg Tablet

Prescription required. May be split. Product of Turkey. Shipped from Mauritius. Gleevec is also marketed internationally under the name Glivec.

This item is backorded. May require additional wait time.

Glivec
400mg Tablet

Prescription required. May be split. Product of India. Shipped from Mauritius. Gleevec is also marketed internationally under the name Glivec.


Generic equivalents for Gleevec... What are generics?

Imatinib Mesylate
100mg Capsule

Prescription required. Can not be split. Product of New Zealand. Shipped from New Zealand.

Imatinib Mesylate
400mg Tablet

Prescription required. May be split. Product of Canada. Shipped from Canada.


To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. read more


Imatinib Mesylate Information

Imatinib (i mat' in ib) Gleevec®

Imatinib is used to treat certain types of leukemia (cancer that begins in the white blood cells) and other cancers and disorders of the blood cells. Imatinib is also used to treat certain types of gastrointestinal stromal tumors (GIST; a type of tumor that grows in the walls of the digestive passages and may spread to other parts of the body). Imatinib is also used to treat dermatofibrosarcoma protuberans (a tumor that forms under the top layer of skin) when the tumor cannot be removed surgically, has spread to other parts of the body, or has come back after surgery. Imatinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.

Imatinib comes as a tablet to take by mouth. It is usually taken with a meal and a large glass of water once or twice a day. Take imatinib at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take imatinib exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. If you are unable to swallow imatinib tablets, you may place all of the tablets that you need for one dose into a glass of water or apple juice. Use 50 milliliters (a little less than 2 ounces) of liquid for each 100-mg tablet and 100 milliliters (a little less than 4 ounces) of liquid for each 400-mg tablet. Stir with a spoon until the tablets crumble completely and drink the mixture immediately. Do not crush the tablets. If you come touch or come in direct contact with a crushed tablet, wash the area thoroughly. If your doctor has told you to take 800 mg of imatinib, you should take 2 of the 400-mg tablets. Do not take 8 of the 100-mg tablets. The tablet coating contains iron, and you will receive too much iron if you take 8 of the 100-mg tablets. Your doctor may increase or decrease your dose of imatinib during your treatment. This depends on how well the medication works for you and on the side effects you experience. Talk to your doctor about how you are feeling during your treatment. Continue to take imatinib even if you feel well. Do not stop taking imatinib without talking to your doctor.

Before taking imatinib, tell your doctor and pharmacist if you are allergic to imatinib or any other medications. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: acetaminophen (Tylenol), alprazolam (Xanax), amlodipine (Norvasc, in Caduet, Lotrel, Tribenzor, others), atazanavir (Reyataz), atorvastatin (Lipitor, in Caduet), carbamazepine (Carbatrol, Equetro, Tegretol, others), clarithromycin (Biaxin, in Prevpac), cyclosporine (Gengraf, Neoral, Sandimmune), dexamethasone, ergotamine (Ergomar, in Migergot, Cafergot), erythromycin (E.E.S., Eryc, Eryped, others), estazolam, felodipine, fentanyl (Duragesic, Subsys, Fentora, others), fosphenytoin (Cerebyx), indinavir (Crixivan), iron, or iron containing supplements, isradipine, itraconazole (Sporanox), ketoconazole, lovastatin (Altoprev), metoprolol (Lopressor, Toprol XL, in Dutoprol), nefazodone, nelfinavir (Viracept), nicardipine (Cardene), nifedipine (Adalat CC, Procardia, others), nimodipine (Nymalize), nisoldipine (Sular), oxcarbazepine (Oxtellar XR, Trileptal), phenobarbital, phenytoin (Dilantin, Phenytek), pimozide (Orap), primidone (Mysoline), quinidine (in Nuedexta), rifabutin (Mycobutin), rifampin (rifadin, rimactane, in Rifamate, Rifater), ritonavir (Norvir, in Kaletra, Technivie, Viekira), saquinavir (Fortovase, Invirase), simvastatin (Zocor, in Vytorin), sirolimus (Rapamune), tacrolimus (Astagraf XL, Envarsus XR, Prograf), telithromycin, voriconazole (Vfend), triazolam (Halcion), and warfarin (Coumadin, Jantoven) , Other medications may also interact with imatinib, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor what herbal products you are taking, especially St. John's wort. tell your doctor if you have or have ever had heart, lung, thyroid, kidney, or liver disease. tell your doctor if you are pregnant or plan to become pregnant. You should not become pregnant while you are taking imatinib and for 14 days after your final dose. Talk to your doctor about birth control methods that you can use during your treatment. If you become pregnant while taking imatinib, call your doctor. Imatinib may harm the fetus. tell your doctor if you are breastfeeding. You should not breastfeed while you are taking imatinib and for one month after your final dose. if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking imatinib. you should know that imatinib may make you dizzy or drowsy or cause blurred vision. Do not drive a car or operate machinery until you know how this medication affects you.

Do not eat grapefruit or drink grapefruit juice while taking this medication.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Imatinib may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: diarrhea nausea vomiting change in the way things taste mouth sores or swelling inside the mouth loss of appetite weight loss heartburn or indigestion dry mouth headache joint swelling or pain bone pain muscle cramps, spasms, or pain tingling, burning. or prickling feeling on the skin difficulty falling asleep or staying asleep sweating teary eyes pink eye flushing dry skin rash itching nail changes hair loss Some side effects can be serious. If you experience any of these symptoms call your doctor immediately: swelling around the eyes swelling of the hands, feet, ankles, or lower legs sudden weight gain shortness of breath fast, irregular, or pounding heartbeat coughing up pink or bloody mucus increased urination, especially at night chest pain peeling, blistering, or shedding skin yellowing of the skin or eyes blood in the stool unusual bruising or bleeding flu-like symptoms, sore throat, fever, chills, and other signs of infection excessive tiredness or weakness abdominal pain or bloating Imatinib may slow growth in children. Your child's doctor will watch his or her growth carefully. Talk to your child's doctor about the risks of giving imatinib to your child. Imatinib may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to imatinib. Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

The content on this page is for informational and educational purposes only and does not constitute professional medical advice. Patients should not use the information presented on this page for diagnosing a health-related issue or disease. Before taking any medication or supplements, patients should always consult a physician or qualified healthcare professional for medical advice or information about whether a drug is safe, appropriate or effective.