Before taking estrogen and bazedoxifene,
tell your doctor and pharmacist if you are allergic to estrogen (in many hormone replacement and birth control medications), bazedoxifene, any other medications, or any of the ingredients in estrogen and bazedoxifene tablets. Ask your pharmacist or check the manufacturer's information for the patient for a list of the ingredients.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements, you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: certain antibiotics including clarithromycin (Biaxin) and erythromycin (E.E.S, E-Mycin); certain antifungal medications including itraconazole (Sporanox) and ketoconazole (Nizoral); and certain medications for seizures including carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, and phenytoin (Dilantin); thyroid hormone replacement medications; rifampin (Rifadin, Rimactane, in Rifamate), and ritonavir (Norvir, in Kaletra). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
tell your doctor what herbal products you are taking, especially St John's wort.
tell your doctor if you have or have ever had liver disease. Your doctor may tell you not to take estrogen and bazedoxifene.
tell your doctor if you are older than 75 years of age and if you have ever had jaundice (a condition that causes yellowing of the skin or eyes) during pregnancy or during your treatment with an estrogen product. Also tell your doctor if you have or have ever had asthma, diabetes, epilepsy, migraine headaches porphyria (condition in which abnormal substances build up in the blood and cause problems with the skin or nervous system), hereditary angioedema (inherited condition that causes episodes of swelling in the hands, feet, face, airway, or intestines), hypoparathyroidism (condition in which the body does not produce enough parathyroid hormone), or kidney disease.
tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking estrogen and bazedoxifene, call your doctor immediately. Estrogen and bazedoxifene may harm the fetus.
if you are taking estrogen to prevent osteoporosis, talk to your doctor about other ways to prevent the disease such as exercising and taking vitamin D and/or calcium supplements.