Qualaquin (Quinine Sulfate)
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Important Notice: Qualaquin (Quinine Sulphate) Not available for sale. Consult with your Family Practitioner for alternative therapy
Quinine Sulfate Information
(kwye' nine)Quinine should not be used to treat or prevent nighttime leg cramps. Quinine has not been shown to be effective for this purpose, and may cause serious or life-threatening side effects, including severe bleeding problems, kidney damage, irregular heartbeat, and severe allergic reactions.
Before taking quinine,
- tell your doctor and pharmacist if you are allergic to quinine, quinidine, mefloquine (Lariam), any other medications, or any of the ingredients in quinine capsules. Ask your doctor or pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: acetazolamide (Diamox); aminophylline; anticoagulants ('blood thinners') such as warfarin (Coumadin) and heparin; antidepressants ('mood elevators') such as desipramine; certain antifungals such as fluconazole (Diflucan), ketoconazole (Nizoral), and itraconazole (Sporanox); cholesterol-lowering medications such as atorvastatin (Lipitor), lovastatin (Mevacor), simvastatin (Zocor); cisapride (Propulsid); dextromethorphan (a medication in many cough products); fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available in the U.S.), levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), ofloxacin (Floxin), and sparfloxacin (Zagam) (not available in the U.S.); macrolide antibiotics such as erythromycin (E.E.S., E-Mycin, Erythrocin) and troleandomycin (not available in the U.S.); medications for diabetes such as repaglinide (Prandin); medications for high blood pressure; medications for irregular heartbeat such as amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), procainamide (Procanbid, Pronestyl), quinidine, and sotalol (Betapace); certain medications for seizures such as carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), and phenytoin (Dilantin); medications for ulcers such as cimetidine (Tagamet); mefloquine (Lariam); metoprolol (Lopressor, Toprol XL); paclitaxel (Abraxane, Taxol); pimozide (Orap); rifampin (Rifadin, Rimactane); certain selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), and paroxetine (Paxil); sodium bicarbonate; tetracycline; and theophylline. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with quinine, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- do not take antacids that contain magnesium or aluminum (Alternagel, Amphogel, Alu-cap, Alu-tab, Basaljel, Gaviscon, Maalox, Milk of Magnesia, or Mylanta) at the same time as you take quinine.Talk to your doctor or pharmacist about how long you should wait between taking this type of antacid and taking quinine.
- tell your doctor if you or anyone in your family has or has ever had a prolonged QT interval (a rare heart problem that may cause fainting or irregular heartbeat), an abnormal electrocardiogram (ECG; a test that measures the electrical activity of the heart), and if you have or have ever had G-6-PD deficiency (an inherited blood disease), or if you have or have ever had myasthenia gravis (MG; condition that causes weakness of certain muscles), or optic neuritis (inflammation of the optic nerve that may cause sudden changes in vision). Also tell your doctor if you have ever had a serious reaction, especially a bleeding problem or problems with your blood after taking quinine in the past. Your doctor will probably tell you not to take quinine.
- tell your doctor if you have or have ever had a slow or irregular heartbeat; low levels of potassium in your blood; or heart, kidney, or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking quinine, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking quinine.
- tell your doctor if you use tobacco products. Cigarette smoking may decrease the effectiveness of this medication.
- difficulty hearing or ringing in the ears
- difficulty breathing or swallowing
- swelling of the face, throat, lips, eyes, hands, feet, ankles or lower legs
- stomach pain
- blurriness or changes in color vision
- inability to hear or see
- easy bruising
- purple, brown, or red spots on the skin
- unusual bleeding
- blood in the urine
- dark or tarry stools
- bleeding gums
- sore throat
- fast or irregular heartbeat
- chest pain