Saxenda (Liraglutide Recombinant)
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Liraglutide Recombinant Information
(lir'' a gloo' tide)Liraglutide injection may increase the risk that you will develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). Laboratory animals who were given liraglutide developed tumors, but it is not known if this medication increases the risk of tumors in humans.Tell your doctor if you or anyone in your family has or has ever had MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2; condition that causes tumors in more than one gland in the body). If so, your doctor will probably tell you not to use liraglutide injection. If you experience any of the following symptoms, call your doctor immediately: lump or swelling in the neck; hoarseness; difficulty swallowing; or shortness of breath. Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests to check your body's response to liraglutide injection. Talk to your doctor about the risks of using liraglutide injection.
Before using liraglutide injection,
- tell your doctor and pharmacist if you are allergic to liraglutide, any other medications, or any of the ingredients in liraglutide injection. Ask your pharmacist or check the Medication Guide for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. It is especially important to tell your doctor about all the medications you take by mouth because liraglutide may change the way your body absorbs these medications. Also tell your doctor about other incretin mimetics such as albiglutide (Tanzeum; no longer available in the US) dulaglutide (Trulicity), exenatide (Bydureon, Byetta), lixisenatide (Adlyxin, in Soliqua), or semaglutide (Ozempic); insulin; or oral medications for diabetes, such as sulfonylureas, including chlorpropamide, glimepiride (Amaryl, in Duetact), glipizide (Glucotrol), glyburide (DiaBeta, Glynase), tolazamide, and tolbutamide. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you drink or have ever drunk large amounts of alcohol, if you have or have ever had depression, thought about or attempted suicide, changes in behavior, pancreatitis (inflammation of the pancreas); severe stomach problems, including gastroparesis (slowed movement of food from the stomach to the small intestine), problems digesting food; a high level of triglycerides (fats) in the blood; gallstones (solid deposits that form in the gallbladder); or gallbladder, kidney or liver disease. Also tell your doctor if you have recently had diarrhea, nausea, or vomiting or if you cannot drink liquids by mouth, which may cause dehydration (loss of a large amount of body fluids).
- tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you are pregnant you should not use liraglutide injection (Saxenda) for weight loss. If you become pregnant while using liraglutide injection (Victoza), call your doctor.
- ask your doctor what to do if you get sick, develop an infection or fever, experience unusual stress, or are injured. These conditions can affect your blood sugar and the amount of liraglutide you may need.
- runny nose, sneezing, or cough
- difficulty urinating or pain or burning on urination
- injection site rash or redness
- ongoing pain that begins in the upper left or middle of the stomach but may spread to the back
- new or worsening depression
- thinking about harming or killing yourself
- clay-colored stools
- yellow eyes or skin
- heart pounding
- fainting or feeling dizzy
- swelling of the eyes, face, mouth, tongue, or throat
- difficulty breathing or swallowing