Skelid (Tiludronate Disodium)
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Tiludronate Disodium Information
(tye loo' droe nate)
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Before taking tiludronate,
- tell your doctor and pharmacist if you are allergic to tiludronate, any other medications, or any of the ingredients in tiludronate tablets. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: chemotherapy medications for cancer and oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone).Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- if you are taking aspirin, indomethacin (Indocin), or calcium or mineral supplements, take them 2 hours before or 2 hours after you take tiludronate. If you are taking antacids containing calcium, magnesium, or aluminum (Maalox, Mylanta, Tums, others), take them at least 2 hours after you take tiludronate.
- tell your doctor if you are unable to stand or sit upright for at least 30 minutes after taking tiludronate. Your doctor will probably tell you not to take tiludronate.
- tell your doctor if you are undergoing radiation therapy and if you have or have ever had difficulty or pain when swallowing; heartburn, ulcers, or other problems with your stomach or esophagus (tube connecting the mouth to the stomach); anemia (condition in which the red blood cells do not bring enough oxygen to all the parts of the body); cancer; any type of infection, especially in your mouth; problems with your mouth, teeth, or gums; any condition that stops your blood from clotting normally; or dental or kidney disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. Also tell your doctor if you plan to become pregnant at any time in the future, because tiludronate may remain in your body for years after you stop taking it. Call your doctor if you become pregnant during or after your treatment.
- you should know that tiludronate may cause serious problems with your jaw, especially if you have dental surgery or treatment while you are taking the medication.A dentist should examine your teeth and perform any needed treatments before you start to take tiludronate. Be sure to brush your teeth and clean your mouth properly while you are taking tiludronate. Talk to your doctor before having any dental treatments while you are taking this medication.
- you should know that tiludronate may cause severe bone, muscle, or joint pain. You may begin to feel this pain within days, months, or years after you first take tiludronate. Although this type of pain may begin after you have taken tiludronate for some time, it is important for you and your doctor to realize that it may be caused by tiludronate. Call your doctor right away if you experience severe pain at any time during your treatment with tiludronate. Your doctor may tell you to stop taking tiludronate and your pain may go away after you stop taking the medication.
- nausea
- vomiting
- diarrhea
- gas
- swelling of the arms, hands, feet, ankles, or lower legs
- pain, burning, numbness, or tingling in the hands or feet
- red or irritated eyes
- changes in vision
- rash
- new or worsening heartburn
- difficulty swallowing
- pain on swallowing
- chest pain