Vantas (Histrelin Acetate)
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Histrelin Acetate Information
(his trel' in)
Before receiving histrelin implant,
- tell your doctor and pharmacist if you are allergic to histrelin, goserelin (Zoladex), leuprolide (Eligard, Lupaneta Pack, Lupron), nafarelin (Synarel), triptorelin (Trelstar, Triptodur Kit), anesthetics such as lidocaine (Xylocaine), any other medications, or any of the ingredients in histrelin implant. Ask your pharmacist for a list of the ingredients.
- tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: amiodarone (Nexterone, Pacerone), anagrelide (Agrylin), bupropion (Aplenzin, Forfivo,Wellbutrin, Zyban, in Contrave), chloroquine, chlorpromazine, cilostazol, ciprofloxacin (Cipro), citalopram (Celexa), clarithromycin, disopyramide (Norpace), dofetilide (Tikosyn), donepezil (Aricept), dronedarone (Multaq), escitalopram (Lexapro), flecainide (Tambocor), fluconazole (Diflucan), fluoxetine (Prozac, Sarafem, Selfemra, in Symbyax), fluvoxamine (Luvox), haloperidol (Haldol), ibutilide (Corvert), levofloxacin, methadone (Dolophine, Methadose), moxifloxacin (Avelox), ondansetron (Zuplenz, Zofran), paroxetine (Brisdelle, Paxil, Pexeva), pentamidine (Pentam), pimozide (Orap), procainamide, quinidine (in Nuedexta), sertraline (Zoloft), sotalol (Betapace, Sorine, Sotylize), thioridazine, vilazodone (Viibryd), and vortioxetine (Trintellix). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with histrelin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
- tell your doctor if you have a low level of potassium or magnesium in your blood. or if you have or have ever had diabetes, high blood pressure, high cholesterol, a prolonged QT interval (a rare heart problem that may cause irregular heartbeat, fainting, or sudden death), cancer that has spread to the spine (backbone), urinary obstruction (blockage that causes difficulty urinating), seizures, brain or blood vessel problems or tumors, mental illness, or heart disease.
- you should know that histrelin is not to be used in women who are pregnant or can become pregnant. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you think you have become pregnant while receiving histrelin implant, call your doctor immediately. Histrelin implant can harm the fetus.
- bruising, soreness, tingling, or itching at the place where implant was inserted
- scarring at the place where implant was inserted
- hot flashes (a sudden wave of mild or intense body heat)
- light vaginal bleeding in girls
- enlarged breasts
- decrease in size of testicles
- decreased sexual ability or interest
- weight gain
- difficulty falling asleep or staying asleep
- crying, irritability, impatience, anger, aggressive behavior
- pain, bleeding, swelling, or redness at the place where implant was inserted
- difficulty breathing or swallowing
- bone pain
- weakness or numbness in the legs
- pain, burning, or tingling in an arm or leg
- slow or difficult speech
- dizziness or fainting
- chest pain
- pain in the arms, back, neck, or jaw
- loss of ability to move
- difficult urination or can not urinate
- blood in urine
- decreased urination
- unusual bleeding or bruising
- extreme tiredness
- loss of appetite
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- flu-like symptoms
- depression, thinking about killing yourself or planning or trying to do so