Varubi (Rolapitant)

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Rolapitant Information

ROLAPITANT (roe LA pi tant) is used with other medicines to prevent nausea and vomiting caused by cancer treatment (chemotherapy).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

They need to know if you have any of these conditions: -liver disease -an unusual or allergic reaction to rolapitant, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Usually, you will take it one hour before your chemotherapy begins. This medicine may be taken with or without food. Do not take more often than directed. Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. NOTE: This medicine is only for you. Do not share this medicine with others.

If you miss a dose, take it as soon as you can. Do not take double or extra doses.

Do not take this medicine with any of these medicines: -pimozide -thioridazine This medicine may also interact with the following medications: -certain medicines for blood pressure, heart disease, irregular heart beat -certain medicines for depression, anxiety, or psychotic disturbances -certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, fosphenytoin -certain medicines that treat or prevent blood clots like warfarin and dabigatran -cyclosporine -dextromethorphan -digoxin -irinotecan -methotrexate -narcotic medicines for pain rifampin -rosuvastatin -sirolimus -topotecan

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

Do not take this medicine if you already have nausea and vomiting. Ask your health care provider what to do if you already have nausea. This medicine should not be used continuously for a long time.

Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -dizziness -signs of decreased red blood cells - unusually weak or tired, feeling faint or lightheaded, falls -signs and symptoms of infection like fever or chills; cough; sore throat; pain or trouble passing urine Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -hiccups -loss of appetite -mouth sores -stomach pain -weight loss

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Keep out of the reach of children. Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.

Rolapitant Oral tablet